An Uncommon Case of Hyperammonemic Encephalopathy

NCJ_cover.jpgBy Valerio Frazzini, Margherita Capasso, Marco Onofrj

First Online: 25 April 2019

Hyperammonemic encephalopathy (HE) associated with urinary tract infections represents a rare but severe neurologic condition [1, 2]. Increased production of ammonia and uptake in the bloodstream upon urinary infections is considered the result of the metabolic activity of urea-splitting bacteria like the Proteus and Corynebacterium strains [2]. However, hyperammonemia has also been rarely reported to occur upon urinary infections sustained by bacteria such as the Providencia rettgeri. HEs associated with P. rettgeri have been described in children presenting massively dilated upper urinary tracts, such as in the prune-belly syndrome [3].

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