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Intracranial Pressure Threshold Heuristics in Traumatic Brain Injury: One, None, Many!

By Christos Lazaridis, Masoom Desai, George Damoulakis & Frederick A. Zeiler First Online: 05 March 2020 Critical care of the patient with severe traumatic brain injury (TBI) revolves around strategies to address intracranial hypertension (IHT), and optimizing cerebral perfusion....

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A Perspective from the Neurocritical Care Society and the Society of Critical Care Medicine: Team-Based Care for Neurological Critical Illness

By Lewis Kaplan, Asma M. Moheet, Sarah L. Livesay, J. Javier Provencio, Jose I. Suarez, Mary Kay Bader, Heatherlee Bailey & Cherylee W. J. Chang First Online: 10 February 2020 The Neurocritical Care Society and the Society of Critical Care Medicine have worked together to create a...

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Key Points to Consider When Evaluating Andexxa for Formulary Addition

By Harry Peled, Nhu Quyen Dau, Helen Lau First Online: 22 October 2019 In May 2018, Andexxa (coagulation factor Xa [recombinant], inactivated-zhzo or formerly andexanet alfa) received accelerated approval from the Food and Drug Administration (FDA) as a specific reversal for rivaroxaban-...

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A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol

By Raffaele Aspide, Giacomo Bertolini, Luca Albini Riccioli, Diego Mazzatenta, Giorgio Palandri, Daniele Guerino Biasucci First Online: 03 October 2019 Measuring and monitoring of intracranial pressure is considered standard of care in patients with suspected intracranial hypertension....

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High-Dose Intravenous Ascorbic Acid: Ready for Prime Time in Traumatic Brain Injury?

By Stefan W. Leichtle, Anand K. Sarma, Micheal Strein, Vishal Yajnik, Dennis Rivet, Adam Sima, Gretchen M. Brophy First Online: 22 August 2019 Traumatic brain injury (TBI) is one of the leading public health problems in the USA and worldwide. It is the number one cause of death and...