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Accuracy of CSF Lactate for Neurologic Outcome in Survivors of Cardiac Arrest

By Justin H. Granstein, Kate Kerpen, Alexandra S. Reynolds & Spyridoula Tsetsou First Online: 18 May 2021 Comatose survivors of out-of-hospital cardiac arrest in the intensive care unit are increasing as a result of advancements in prehospital resuscitation [1]. Timely, accurate...


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Role of Neurostimulants During Acute Stroke Care: Do they Improve Wakefulness?

By Prateek Kumar Panda, Anju Mehra & Indar Kumar Sharawat First Online: 12 May 2021 We read with great interest the recently published article titled “Amantadine and Modafinil as Neurostimulants Following Acute Stroke: A Retrospective Study of Intensive Care Unit Patients” by Leclerc et...


Blog Entry
Precise Clinical Outcome in High-Grade Aneurysmal Subarachnoid Hemorrhage: Brain Oxygenation Matters!

By Johan Schmitt, Philippe Aries, Marc Danguy Des Deserts & Christophe Giacardi First Online : 27 April 2021 Wettervik et al. [1] recently published a great work titled “Temporal Dynamics of ICP, CPP, PRx, and CPPopt in High-Grade Aneurysmal Subarachnoid Hemorrhage and the Relation to...


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Communication and Well-Being Considerations in Disorders of Consciousness

By Christos Lazaridis, Masoom Desai & L. Syd M. Johnson First Online : 21 January 2021 The manuscript by Provencio et al. describes the proceedings of the first Curing Coma Campaign Scientific Advisory Council meeting and discusses three major pillars for future investigation: endotyping...


Blog Entry
Response from Rajat Dhar to Letter to the Editor

By Rajat Dhar First Online: 22 September 2020 This letter is in response to this letter to the editor https://doi.org/10.1007/s12028-020-01102-2 regarding the article available at https://doi.org/10.1007/s12028-020-01056-5. We would like to thank Diprose and colleagues for their...


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The Authors Reply: Correlation Between Ultrasonographic Optic Nerve Sheath Diameter and Intracranial Pressure in Patients with Aneurysmal Subarachnoid Hemorrhage

By Alessio Caccioppola, Tommaso Zoerle & Nino Stocchetti First Online: 21 September 2020 Dear Editor, We thank Dr. Varun Suresh and colleagues for their comments on our recent paper [1] suggesting different pathophysiological mechanisms that could explain the poor relationship between...


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Intracranial Reserve in Ischemic Stroke: Is the Skull Half-Full or Half-Empty?

By William K. Diprose, James P. Diprose, Michael T. M. Wang & P. Alan Barber First Online: 21 September 2020 This comment refers to the article available at https://doi.org/10.1007/s12028-020-01105-z, https://doi.org/10.1007/s12028-020-01056-5. We read with interest the article ...


Blog Entry
Correlation Between Ultrasonographic Optic Nerve Sheath Diameter and Intracranial Pressure in Patients with Aneurysmal Subarachnoid Hemorrhage

By Varun Suresh, Saurabh Sharma & Anurag Aggarwal First Online: 21 September 2020 We read with interest the research work published by Zoerle et al. [1] on correlation between optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in patients with intracranial aneurysm...


Blog Entry
Updated Nomenclature of Delirium and Acute Encephalopathy

By Arjen J. C. Slooter & Robert D. Stevens First Online: 12 August 2020 We read with interest the article by Singh et al. on acute encephalopathy as an adverse effect of the cephalosporin cefepime [1]. The authors state that they follow recent recommendations on the terminology of...


Blog Entry
Hyperosmolar Agents for TBI: All Are Equal, But Some Are More Equal Than Others?

By H. Quintard, G. Meyfroidt & G. Citerio First Online: 07 August 2020 We read with interest the guidelines for the acute treatment of cerebral edema in neurocritical care patients published by Cook et al. [1] and congratulate the authors for their work. Brain edema is a major...