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Serum Glial Fibrillary Acidic Protein in Acute Stroke

By David B. Seder First Online: 05 March 2020 Until now, serum biomarkers of brain injury have not had a role in the critical care management of acute stroke. This is due in part to biology; proteins spilled after brain or spinal cord injury are not immediately released from damaged...


Blog Entry
“Take a Number”—Precision Monitoring Directs Precision Therapy

By Patrick M. Kochanek, Ruchira M. Jha & Robert S. B. Clark First Online: 05 March 2020 Over the years, defining the “optimal” intracranial pressure (ICP) threshold to intervene with a single number has served to help guide the field of neurocritical care to manage complex disorders,...


Blog Entry
Are Direct Anticoagulants Safer in Traumatic Brain Injury Compared to Warfarin?

By Katja E. Wartenberg First Online: 24 February 2020 Increasing application of direct oral anticoagulants (DOACs) requires new insight into management concepts in traumatic brain injury (TBI). Isolated TBI is more frequently seen in the elderly population [1] which is at higher risk for...


Blog Entry
Ready or Not (To Apply)? Autoregulatory Dysfunction Indices and Lesion Progression in Traumatic Brain Injury

By Susanne Muehlschlegel First Online: 16 December 2019 When it comes to intracranial pressure (ICP) and cerebral perfusion pressure (CPP) targets in traumatic brain injury (TBI), the notion that “one size does not fit all” has been displayed by several important studies. For example,...


Blog Entry
Commentary on Associations of Radiographic Small Vessel Disease with Acute Intracerebral Hemorrhage Volume, Hematoma Expansion, and Intraventricular Hemorrhage

By Sarah E. Nelson First Online: 03 December 2019 Venema et al. [1] performed a study based on Ethnic and Racial Variations in Intracerebral Hemorrhage, a multicenter, racially balanced, prospective study of spontaneous intracerebral hemorrhage (ICH). The authors hypothesize that underlying...


Blog Entry
Invited Editorial Commentary: More Than One Way to Treat the Mass Effect

By Daniel F. Hanley, Yunke Li First Online: 09 December 2019 Unproven concepts about the value of decompressive craniectomy (DC) for intracerebral hemorrhage (ICH) may be arising from its use with large ischemic stroke [1, 2]. Ye et al. [3] present a retrospective study comparing endoscopic...


Blog Entry
Neurocritical Care: A Growing International Collaborative

By Andreas H. Krame, Philippe Couillard First Online: 30 September 2019 Patients with neurological conditions account for at least 10–15% of admissions to intensive care units (ICUs) [1]. In addition, many critically ill patients with sepsis or respiratory failure develop neurological...


Blog Entry
Intervascular Line Infections: Can We Prevent Them? Bring on the Team!

By Peter J. Papadakos First Online: 27 September 2019 Central venous catheters (CVCs) and peripherally inserted central catheters (PICCs) are essential tools in the care of critically ill intensive care unit (ICU) patients. They allow for administration of large amounts of intravenous...


Blog Entry
Predicting Malignant Cerebral Edema After Large Hemispheric Stroke

By W. Taylor Kimberly First Online: 23 September 2019 Large hemispheric infarction (LHI) is an ischemic stroke of the middle cerebral artery (MCA) territory and leads to a disproportionate degree of disability and death [1, 2]. Poor functional outcome is further exacerbated when severe...


Blog Entry
Burnout and Resiliency Among Neurocritical Care Staff; Potential Solutions to A Growing Problem

By Ana-Maria Vranceanu First Online: 13 August 2019 Over the past decade, there has been a proliferation of research on psychosocial sequelae associated with hospitalization for neurocritical illness for both patients and their informal caregivers (e.g., family and friends who provide...