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Neuromonitoring: No Longer a Spectator Sport

By Eric S. Rosenthal First Online: 06 April 2020 Seizure diagnosis is a fundamentally challenging issue in neurocritical care. The vast majority of seizures detected by electroencephalography (EEG) are nonconvulsive [1], yet the yield of scalp EEG is limited without concomitant...


Blog Entry
What is the Role of Continuous Electroencephalography in Acute Ischemic Stroke and the Relevance of the “Ictal-Interictal Continuum”?

By Andreas Kramer & Julie Kromm First Online: 03 April 2020 Acute ischemic stroke (AIS) is the primary diagnosis in about 5% of patients admitted to neurocritical care units in North America [1]. Convulsive seizures occur in approximately 5% of patients with AIS [2, 3], of which 10–20%...


Blog Entry
Cheap and Cheerful: Early Initiation of Oral Antihypertensives After ICH Saves Time and Money

By Jennifer A. Frontera First Online: 30 March 2020 The INTERACT2 and ATACH-II trials, both large, international, multi-center, randomized-controlled trials, evaluated the benefits of early aggressive blood pressure control following spontaneous intracerebral hemorrhage (ICH) [1, 2]. While...


Blog Entry
Location, Location, Location: The Rural–Urban Divide in Intracerebral Hemorrhage Mortality

By Roland Faigle First Online: 30 March 2020 Inequities in healthcare quality and outcomes are pervasive in the USA. Geographic location has been increasingly recognized as an important, and arguably modifiable, determinant of health. Approximately 15–20% of the US population live in rural...


Blog Entry
Long-Term Outcome and Economic Burden of Aneurysmal Subarachnoid Hemorrhage: Are we Only Seeing the Tip of the Iceberg?

By Shane W. English First Online: 20 March 2020 Aneurysmal subarachnoid hemorrhage (SAH) remains a devastating form of stroke that affects a particularly young and often otherwise healthy population. It is associated with significant morbidity and premature mortality with a typical...


Blog Entry
Serum Glial Fibrillary Acidic Protein in Acute Stroke

By David B. Seder First Online: 05 March 2020 Until now, serum biomarkers of brain injury have not had a role in the critical care management of acute stroke. This is due in part to biology; proteins spilled after brain or spinal cord injury are not immediately released from damaged...


Blog Entry
“Take a Number”—Precision Monitoring Directs Precision Therapy

By Patrick M. Kochanek, Ruchira M. Jha & Robert S. B. Clark First Online: 05 March 2020 Over the years, defining the “optimal” intracranial pressure (ICP) threshold to intervene with a single number has served to help guide the field of neurocritical care to manage complex disorders,...


Blog Entry
Are Direct Anticoagulants Safer in Traumatic Brain Injury Compared to Warfarin?

By Katja E. Wartenberg First Online: 24 February 2020 Increasing application of direct oral anticoagulants (DOACs) requires new insight into management concepts in traumatic brain injury (TBI). Isolated TBI is more frequently seen in the elderly population [1] which is at higher risk for...


Blog Entry
Ready or Not (To Apply)? Autoregulatory Dysfunction Indices and Lesion Progression in Traumatic Brain Injury

By Susanne Muehlschlegel First Online: 16 December 2019 When it comes to intracranial pressure (ICP) and cerebral perfusion pressure (CPP) targets in traumatic brain injury (TBI), the notion that “one size does not fit all” has been displayed by several important studies. For example,...


Blog Entry
Commentary on Associations of Radiographic Small Vessel Disease with Acute Intracerebral Hemorrhage Volume, Hematoma Expansion, and Intraventricular Hemorrhage

By Sarah E. Nelson First Online: 03 December 2019 Venema et al. [1] performed a study based on Ethnic and Racial Variations in Intracerebral Hemorrhage, a multicenter, racially balanced, prospective study of spontaneous intracerebral hemorrhage (ICH). The authors hypothesize that underlying...