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How Does the Brain Die After a Massive Posterior Fossa Lesion?

By Chris Marcellino, Sherri A. Braksick & Eelco F. M. Wijdicks First online: 02 December 2020 A devastating neurological complication occurred [1,2,3,4] as a result of the hypercoagulability of COVID-19 pneumonia [5]. An ischemic stroke (or perhaps venous sinus thrombosis) involved...


Blog Entry
COVID-19-Associated Acute Multi-infarct Encephalopathy in an Asymptomatic CADASIL Patient

By Tianshu Zhang, Ellen Hirsh, Shadi Zandieh & Michael B. Rodricks First Online: 06 October 2020 COVID-19 is a new disease caused by the SARS-CoV-2 virus. First described in Wuhan, China, the scope and speed with which the disease has spread has placed healthcare systems around the...


Blog Entry
Lid and Convergence Retraction Nystagmus in Thalamic–Midbrain Hematoma

By Kristen M. Scheitler, Rafid Mustafa & Eelco F. M. Wijdicks First Online: 02 July 2020 Convergence retraction nystagmus, while non-prognostic, localizes to the dorsal midbrain posterior commissure and underscores the severity of hematoma extension in this patient. Characteristically,...


Blog Entry
A Punch to the Gut from a Ruptured Cerebral Aneurysm

By Tia Chakraborty & Eelco Wijdicks First Online: 30 March 2020 Introduction There are a myriad of complications of aneurysmal subarachnoid hemorrhage (SAH). Systemic effects include hyponatremia, stunned myocardium (takotsubo cardiomyopathy), pulmonary edema, deep venous...


Blog Entry
Transient Intracranial Circulatory Arrest Evidenced at the Time of Intracranial Aneurysm Rupture: Case Report

By Ilari Rautalin & Miikka Korja First Online: 26 March 2020 One-fourth of people with aneurysmal subarachnoid hemorrhage (SAH) die from the bleed suddenly in emergency rooms or before reaching hospital [1]. Unless medicolegal or medical autopsies are systematically performed to all...


Blog Entry
Another Pitfall in Brain Death Diagnosis: Return of Cerebral Function After Determination of Brain Death by Both Clinical and Radionuclide Cerebral Perfusion Imaging

By Julius Gene S. Latorre, Elena B. Schmidt & David M. Greer First Online: 10 March 2020 Introduction Brain single-photon emission computed tomography (SPECT) is a noninvasive ancillary test used in selected patients in the determination of brain death (BD) with reported...


Blog Entry
Multiple Brain Abscesses Due to Odontogenic Infection

By Nicolas Alejandro Gemelli, Luis Alejandro Boccalatte & Nicolas Marcelo Ciarrocchi First Online: 31 January 2020 References 1. Belkacem A, Caseris M, Yazdanpanah Y. A case of Aggregatibacter aphrophilus multiple abscess. Open Forum Inf Dis. 2015;2(2):ofv031. 2. Nørskov N....


Blog Entry
Brushing Against the Tentorium: Traumatic Pseudoaneurysm of the Posterior Cerebral Artery

By Charlotte E. Dujardin, Harry Cloft, Eelco F. M. Wijdicks First Online: 18 November 2019 Both blunt and penetrating traumatic brain injury (TBI) may cause damage to the intracranial vasculature. Blunt force brings about sudden deceleration, and injury may develop in arteries that are in...


Blog Entry
A Young Woman Presenting with Encephalopathy: A Case Report

By Mario Kofler, Stefan Kiechl, Raimund Helbok First Online: 01 November 2019 When cerebral white matter lesions are detected in young patients presenting with neurologic symptoms, the most likely diagnosis is multiple sclerosis (MS). Still, it is crucial to screen for important differential...


Blog Entry
Regional Cerebral Hypoperfusion from Acute Subdural Hematoma

By Natsumi T. Hamahata, Kazuma Nakagawa First Online: 01 November 2019 A large acute subdural hematoma (SDH) may result in regional brain compression, elevated intracranial pressure and cerebral hypoperfusion, which could ultimately lead to secondary brain injury. The severity of this...