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Optimal Targets of the First 24-h Partial Pressure of Carbon Dioxide in Patients with Cerebral Injury: Data from the MIMIC-III and IV Database

By: Gengxin Cai, Xiunong Zhang, Qitian Ou, Yuan Zhou, Linqiang Huang, Shenglong Chen, Hongke Zeng, Wenqiang Jiang & Miaoyun Wen First Online: 30 July 2021 Background It is generally believed that hypercapnia and hypocapnia will cause secondary injury to patients with craniocerebral...


Blog Entry
Dynamic Intracranial Pressure Waveform Morphology Predicts Ventriculitis

By: Murad Megjhani, Kalijah Terilli, Lakshman Kalasapudi, Justine Chen, John Carlson, Serenity Miller, Neeraj Badjatia, Peter Hu, Angela Velazquez, David J. Roh, Sachin Agarwal, Jan Claassen, E. S. Connolly Jr., Xiao Hu, Nicholas Morris & Soojin Park First Online: 30 July 2021 ...


Blog Entry
A One-Day Prospective National Observational Study on Sedation-Analgesia of Patients with Brain Injury in French Intensive Care Units: The SEDA-BIP-ICU (Sedation-Analgesia in Brain Injury Patient in ICU) Study

By: Simon Poignant, Bernard Vigué, Patricia Balram, Mathieu Biais, Romain Carillon, Vincent Cottenceau, Claire Dahyot-Fizelier, Vincent Degos, Thomas Geeraerts, Patrick Jeanjean, Emmanuel Vega, Sigismond Lasocki, Fabien Espitalier, Marc Laffon & ANARLF and AtlanRea Network for the SEDABIP...


Blog Entry
Brain Temperature Influences Intracranial Pressure and Cerebral Perfusion Pressure After Traumatic Brain Injury: A CENTER-TBI Study

By: Tatiana Birg, Fabrizio Ortolano, Eveline J. A. Wiegers, Peter Smielewski, Yan Savchenko, Bogdan A. Ianosi, Raimund Helbok, Sandra Rossi, Marco Carbonara, Tommaso Zoerle, Nino Stocchetti & the CENTER-TBI Investigators and Participants First Online: 30 July 2021 Background After...


Blog Entry
Evaluation of Seizure Risk in Infants After Cardiopulmonary Bypass in the Absence of Deep Hypothermic Cardiac Arrest

By: Rebecca J. Levy, Elizabeth W. Mayne, Amanda G. Sandoval Karamian, Mehreen Iqbal, Natasha Purington, Kathleen R. Ryan & Courtney J. Wusthoff First Online: 28 July 2021 Background Guidelines recommend evaluation for electrographic seizures in neonates and children at risk,...


Blog Entry
Impact of Increased Hemoglobin on Spontaneous Intracerebral Hemorrhage

By: 27 July 2021 First Online: Yuxuan Lu, Haiqiang Jin, Yuhua Zhao, Yuxian Li, Jun Xu, Jiayu Tian, Xiaoting Luan, Siwei Chen, Wei Sun, Shouzi Zhang, Shunliang Xu, Feiqi Zhu, Luzeng Chen, Dunzhu Mima, Yongan Sun & Cidan Zhuoga Background Studies of the impact of increased hemoglobin...


Blog Entry
Risk Factors Associated with ICU-Specific Care in Patients Undergoing Endovascular Treatment of Unruptured Intracranial Aneurysms

By: Varun Padmanaban, Michael Gigliotti, Sonia Majid, Francis J. Jareczek, Chanju Fritch, Sprague W. Hazard, J. Christopher Zacko, Scott D. Simon, Paul Kalapos, Ephraim W. Church, D. Andrew Wilkinson & Kevin M. Cockroft First Online: 26 July 2021 Background Multiple studies suggest...


Blog Entry
Development and Evaluation of a Method for Automated Detection of Spreading Depolarizations in the Injured Human Brain

By: Sharon Jewell, Stephen Hobson, Grant Brewer, Michelle Rogers, Jed A. Hartings, Brandon Foreman, José-Pedro Lavrador, Michael Sole, Clemens Pahl, Martyn G. Boutelle & Anthony J. Strong First Online: 26 July 2021 Spreading depolarizations (SDs) occur in some 60% of patients...


Blog Entry
Making Waves: Will It Help Children with Traumatic Brain Injury?

By: Shruti Agrawal First Online: 15 July 2021 Standardized patient care through a steady evolution of protocols, guidelines and care bundles has improved survival from disease. With improved survival, the focus has shifted to reducing morbidity and improving quality of life, especially...


Blog Entry
Seizures in Children with Cardiac Disease on Extracorporeal Membrane Oxygenation

By: Daniel O. Hassumani, Mu Shan, Christopher W. Mastropietro, Sarah E. Wing & Matthew L. Friedman First Online: 15 July 2021 Background Children supported with extracorporeal membrane oxygenation (ECMO) have been shown to be at risk for developing seizures. However, previous...